BDBM50229973 (4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yl)-(3-nitrophenyl)amine::4-methyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)thiazol-2-amine::CHEMBL298445::[4-(2-AMINO-4-METHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-(3-NITRO-PHENYL)-AMINE

SMILES Cc1nc(N)sc1-c1ccnc(Nc2cccc(c2)[N+]([O-])=O)n1

InChI Key InChIKey=DYTKVFHLKPDNRW-UHFFFAOYSA-N

Data  15 KI  7 IC50

PDB links: 3 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229973   

TargetCyclin-dependent kinase 7(Homo sapiens (Human))
Cyclacel

Curated by ChEMBL

LigandBDBM50229973((4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yl)-(...)Copy SMILESCopy InChI

Affinity DataKi:  70nMAssay Description:Inhibition of CDK7More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankGoogleScholar

Ligand InfoPurchaseCHEMBLDrugBankMMDBPC cidPC sidPDBPatentsSimilars

In DepthDetails ArticlePubMed
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